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Top Panama Canal Cruises & Trips

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Explore these 11 top Panama Canal cruises for 2024 and 2025. Some of the most popular activities on our Panama Canal trips include cruises, wildlife viewing, small ship cruises, snorkeling, and beaches. Discover Panama Canal with your expert local English-speaking guides who will show you the hot spots and the off-the-beaten-path hidden gems. We work with only the best small ships that carry under 500 fortunate guests, and we can give you unbiased advice to match you with the perfect ship and perfect cruise for your next vacation. Our Panama Canal cruises start from $3,540 for cruises of 8 to 24 days. Contact one of Adventure Life's Panama Canal cruise specialists for help planning a seamless trip.
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Keel-billed Toucan
$6,054
EXPLORE

Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys

8 Day Itinerary aboard Le Bellot
  • Cross the Panama Canal
  • Punta Culebra Nature Center at STRI
  • Snorkel on beautiful Holandes Cayes
  • See Darién National Park rainforest
Starts / Ends:
Colon / Puerto Caldera
Activities:
Rainforest Exploration, Small Ship Cruises, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
The San Blas Islands of Holandes Cayes, Panama City's Old Quarter, and the Darién National Park are highlights of Le Bellot's journey in Central America. Proceed to Fuente Amador and start your exploration of the Panama Canal. In Costa Rica, you may encounter sloths, the noisy howler …
Cruise Details
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Trekking through Corcovado National Park in Costa Rica.
$6,601
EXPLORE

Costa Rica & the Panama Canal

8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities:
Horseback Riding, Kayaking, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Wildlife Viewing
Activity Level:
Relaxed
Join the National Geographic Quest onthis 8-dayexpedition to Costa Rica and the Panama Canal.Discover diverse wilderness and jungle wildlife coupled with an in-depth crossing of the Panama Canal, a marvel of engineering, and gain special access to the Smithsonian Tropical Research Institute in the …
Cruise Details
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San Blas
$7,090
EXPLORE

Secrets of Central America

11 Day Itinerary aboard Le Bellot
  • Explore Fort San Lorenzo
  • Discover San Blas Islands
  • Experience Panama Canal
  • Swim in the Pearl Islands
Starts / Ends:
Colon / Puntarenas
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Relaxed
Embark on an 11-day expedition cruise from Colon to Puntarenas aboard the Le Bellot. Visit San Lorenzo’s Fort, an extraordinary fortress safeguarding transatlantic trade. Next, explore the San Blas Islands, home to the Kuna people and their vibrant craft of molas. Cross the legendary Panama …
Cruise Details
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Boats Moored to the Quay at Bridgetown Harbour
$4,440
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Gatun Lock of the Panama Canal
$4,440
EXPLORE

Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Transit the historic Panama Canal
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Swim in paradise in Bonaire
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Panama City's Bridge of the Americas
$11,675
EXPLORE

Once through the Panama Canal

Panama to Costa RIca - 11 Day Itinerary aboard Sea Cloud Spirit
  • Cruise through the Panama Canal
  • Encounter islands & national parks
  • Discover Palo Verde National Park
  • Spot Coatis, jaguars and birds
Starts / Ends:
Colon / Puntarenas
Activities:
Wildlife Viewing
Activity Level:
Relaxed
Embark on an 11-day cruise through the historic Panama Canal, start in Panama City and. experience a dinner cruise through the iconic Panama canal, exploring Gatúnsee's unique islands like Barro Colorado in the rainforest. Sail through the canal's 12 lock basins, showcasing its …
Cruise Details
0
Zapatilla Cay, Panama
$6,290
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends:
Panama City / Cartagena
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Relaxed
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coast of Panama and Colombia on this 8-day cruise aboard theNational Geographic Quest. Hike into dense rainforests that harbor extraordinary biodiversity, glide through little-explored inlets by Zodiac and …
Cruise Details
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Get stunning views of historic Cartagena
$13,395
EXPLORE

Costa Rica & Panama Canal

Costa Rica - Colombia - 15 Day Itinerary aboard Greg Mortimer
  • Explore Costa Rica's wildlife
  • Discover vibrant bird species
  • Learn about the Emberá tribe
  • Explore Cartagena de Indias
Starts / Ends:
San Jose / Cartagena
Activities:
Archaeological Site Visits, Photography Seminars, Scuba Diving, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Village Visits, Whale Watching, Wildlife Viewing
Activity Level:
Relaxed
Immerse in the coastal landscapes of Costa Rica and Panama on this 15-day cruise aboard Greg Mortimer with travel photographerRichard I'Anson. Costa Rica stands as one of the world's most biodiverse regions, offering opportunities to explore lush tropical rainforests with a remarkable array …
Cruise Details
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Watching ships pass through the Panama Canal
$6,601
EXPLORE

Costa Rica & Panama Canal Discovery

Punta Arenas - Cartagena - 12 Day Itinerary aboard SH Diana
  • Discover Puntarenas
  • Discover Tortuga, Chira, and Coco
  • Explore Nicoya Peninsula
  • Witness Costa Rica culture
Starts / Ends:
Puntarenas / Cartagena
Activities:
Fishing, Hiking, Small Ship Cruises, Snorkeling, Village Visits
Activity Level:
Relaxed
On this 12-day cruise aboard SH Diana, discover the hidden treasures of Puntarenas, a captivating destination that showcases the authentic and diverse culture of Costa Rica. Nestled on a narrow peninsula stretching into the Pacific Ocean, this vibrant city is a favorite among locals and tourists …
Cruise Details
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Boats Moored to the Quay at Bridgetown Harbour
$3,540
EXPLORE

Barbados to Panama Christmas Cruise

15 Day Itinerary aboard Star Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
Star Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Explore the California coast
$11,850
EXPLORE

San Francisco, California to New York

24 Day Itinerary aboard Silver Shadow
  • Explore the West Coast
  • Experience Cabo San Lucas
  • Visit Acapulco's sandy beaches
  • Explore Aruba and St. Thomas
Starts / Ends:
San Francisco / New York City
Activities:
Hiking, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
This 24-day San Francisco to New York Cruise aboard Silver Shadow offers delightful sea days and breathtaking sights. Passengers set sail from the golden-gated shores of San Francisco, cruising past iconic West Coast scenery until they reach Los Angeles. During a full day in the star-studded city, …
Cruise Details
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