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Top Panama Canal Cruises & Trips

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Explore these 6 top Panama Canal cruises for 2023 and 2024. Some of the most popular activities on our Panama Canal trips include cruises, wildlife viewing, small ship cruises, snorkeling, and small ship sailing. Discover Panama Canal with your expert local English-speaking guides who will show you the hot spots and the off-the-beaten-path hidden gems. We work with only the best small ships that carry under 500 fortunate guests, and we can give you unbiased advice to match you with the perfect ship and perfect cruise for your next vacation. Our Panama Canal cruises start from $2,950 for cruises of 8 to 80 days. Contact one of Adventure Life's Panama Canal cruise specialists for help planning a seamless trip.
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Playa Manuel Antonio
$2,950
EXPLORE

Crossing the Panama Canal: Costa Rica to Panama

Puerto Caldera - Colon - 8 Day Itinerary aboard Panorama
  • Explore the stunning Manuel Antonio
  • Tour Casa Orquidea's flowers
  • Discover the forest and animal life
  • Cross to the Panama Canal
Starts / Ends:
Puerto Caldera / Colon
Activities:
Small Ship Cruises, Snorkeling, Village Visits, Wildlife Viewing
Activity Level:
Relaxed
Experience a harmonious balance between conventional cruising and private yachting, along with an exciting voyage of discovery along the Pacific Ocean coastline of Costa Rica. Explore the Nature Reserves and National Parks of Isla Coiba and Manuel Antonio, witness life in the Darrien Jungle, and …
Cruise Details
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Trekking through Corcovado National Park in Costa Rica.
$6,820
EXPLORE

Costa Rica & the Panama Canal

8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities:
Horseback Riding, Kayaking, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Wildlife Viewing
Activity Level:
Relaxed
Join the National Geographic Quest onthis 8-dayexpedition to Costa Rica and the Panama Canal.Discover diverse wilderness and jungle wildlife coupled with an in-depth crossing of the Panama Canal, a marvel of engineering, and gain special access to the Smithsonian Tropical Research Institute in the …
Cruise Details
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Boats Moored to the Quay at Bridgetown Harbour
$4,370
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
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Gatun Lock of the Panama Canal
$4,370
EXPLORE

Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Transit the historic Panama Canal
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Swim in paradise in Bonaire
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
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Zapatilla Cay, Panama
$6,290
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends:
Panama City / Cartagena
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Relaxed
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coast of Panama and Colombia on this 8-day cruise aboard theNational Geographic Quest. Hike into dense rainforests that harbor extraordinary biodiversity, glide through little-explored inlets by Zodiac and …
Cruise Details
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Colorful canoes await passengers on the river
$43,399
EXPLORE

Grand Americas, Amazon & Antarctica

80 Day Itinerary aboard Seabourn Quest
  • Kayak in Antarctica to see wildlife
  • See Shackleton's grave in Grytviken
  • Enjoy Buzios' tropical beaches
  • See Brazil's Pink river dolphins
  • Explore Carambola beach clubs
Starts / Ends:
Miami / Miami
Activity Level:
Relaxed
Embark on an 80-day Grand Voyage aboard the Seabourn Quest to take in the amazing sights and diverse culture of the Americas, Amazon, and Antarctica.Reflect on the engineering marvel that is the Panama Canal as your ship sails majestically out of the canal and into the Pacific Ocean for your first …
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