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Panama's turquoise waters

Portobelo Panama Cruises

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Experience the captivating beauty and rich history of Portobelo, Panama, with Adventure Life's array of 3 cruises for 2025. Join us on a cruise journey through this historic port town, where you can explore its colonial forts, dive into its vibrant culture, and marvel at its lush landscapes. From snorkeling in crystal-clear waters to hiking through tropical rainforests, each moment offers a unique opportunity to immerse yourself in the wonders of this region. Engage in village visits, wildlife viewing, and archaeological site visits, all while surrounded by the natural splendor that has inspired explorers for centuries. With cruises ranging from , begin your adventure to Portobelo today and contact one of Adventure Life's tour specialists for help planning your next seamless trip.
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    • Portobelo
Tranquil shores and swaying palms welcome you to Cayman Brac
from $4,240
EXPLORE

Panama to Jamaica

Balboa - Montego Bay - 15 Day Itinerary aboard Star Clipper
  • Explore Balboa’s architecture
  • Transit Panama Canal’s locks
  • Discover Portobelo’s Spanish forts
  • Tour Puerto Limon’s markets
Starts / Ends
Balboa / Isla de Providencia
Activities
Archaeological Site Visits, Snorkeling, Local Market Visits, Small Ship Sailing
Activity Level
Variable
Join a 15-day cruise from Balboa to Montego Bay aboard the Star Clippers, sailing through the Panama Canal and exploring cultural gems like Portobelo and Puerto Limon. Relax at sea and visit beautiful beaches in Bocas del Toro and the diving hotspots of George Town and Cayman Brac before concluding your journey in Jamaica.
Cruise Details
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Sunset over Cartagena, Colombia
from $6,810
Save 20%
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends
Panama City / Cartagena
Activities
Village Visits, Stand Up Paddle Boarding, Kayaking, Wildlife Viewing, Hiking
Activity Level
Variable
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, Archipelago, and more.
Cruise Details
0
Mountains by the ocean in St Lucia
from $8,490
EXPLORE

Panama, Colombia & Caribbean Islands

Colon to Fort-de-France - 13 Day Itinerary aboard Le Champlain
  • Sail through the Central America.
  • See San Blas, Bonaire & Grenadines
  • Experience swim and snorkel.
  • Learn traditions of the Kuna people
  • Dive with an experienced instructor
Starts / Ends
Colon / Fort de France
Activities
Land & Sea Exploration
Activity Level
Variable
Join Le Bellot for an exceptional 13-day cruise sailing from Colón to Fort-de-France. This itinerary gives you the opportunity to appreciate the richness and diversity of Afro-Caribbean cultures, an azure blue sky, and white-sand beaches. Visit stunning ports, including Portobelo, Cartagena, Santa Marta, Mayreau Island, and Soufriére.
Cruise Details
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