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Top Mississippi River Trips & Tours in 2022

Travel made your way
New Orleans
Sean Pavone
Visit the famed Bourbon Street
St Louis
Sean Pavone
View the iconic arch when you visit St. Louis, gateway to the west
Vicksburg
Michael Warren
View a Civil War battlefields in Mississippi
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Discover Mississippi River in 2022 on one of these amazing trips hand selected by the travel experts at Adventure Life. Select any of the below 29 top-rated trips where you will explore Memphis, New Orleans, Natchez, Vicksburg, and Nottoway with an exceptional bilingual guide on a small group or customizable private tour. The most popular things to do in Mississippi River in 2022 are river cruises, cruises, cultural, village visits, and urban exploration. Our Mississippi River trips in 2022 range in price from $1,999 to $41,796 for trips of 8 to 16 days. Contact one of Adventure Life's expert Mississippi River trip planners for help planning a seamless experience.
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New Orleans paddlewheel steamer in New Orleans, Lousiana
$2,299
EXPLORE

New Orleans to Memphis

9 Day Itinerary aboard American Queen
  • Explore vibrant New Orleans
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore Nottoway Plantation
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Visit historic St. Louis
$2,559
EXPLORE

Memphis to St. Louis

9 Day Itinerary aboard American Queen
  • Listen to the music of Memphis
  • Explore wonders of New Madrid
  • Admire historic handicrafts
  • Explore the culture of St. Louis
Starts / Ends:
Memphis / St. Louis
Activities:
River Cruises, Village Visits
Activity Level:
Relaxed
Board the American Queen and join this delightful 9-day journey From the legacies that line the Mississippi River to the corners of creative genius along Ohio, your riverboat journey promises a wealth of eye-opening experiences and memories. Explore the seismic wonders of New Madrid and the iconic …
Cruise Details
0
$3,599
EXPLORE

Louisville to St. Louis

9 Day Itinerary aboard American Countess
  • Taste famous Kentucky bourbon
  • Enjoy the music of Owensboro
  • Admire historic handicrafts
  • Explore vibrant St. Louis
Starts / Ends:
Louisville / St. Louis
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Board the American Countess riverboat and cruise through the heart of the American Midwest on this 9-day journey from Louisville, Kentucky to St. Louis, Missouri on the Ohio and Mississippi Rivers. Experience the laid-back, small-town hospitality of Kentucky ports such as Owensboro, where …
Cruise Details
0
Visit historic St. Louis
$2,799
EXPLORE

St. Louis to Minneapolis

9 Day Itinerary aboard American Countess
  • Explore the culture of St. Louis
  • See Mark Twains hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Explore the country and river that inspired Mark Twain, the pen name of the famed American novelist Samuel Clemens. From St. Louis, Missouri, cruise north along the magnificent Mississippi River towards Minneapolis. Explore port towns such as Hannibal, Missouri, the birthplace of Mark Twain, and …
Cruise Details
0
Explore historic New Orleans
$5,399
EXPLORE

Minneapolis to New Orleans

16 Day Itinerary aboard American Queen
  • Enjoy musical history in Memphis
  • Admire the diversity of New Orleans
  • Discover St. Louis, Missouri
  • Explore the arts in Minneapolis, MN
  • Learn about Civil War history
Starts / Ends:
Minneapolis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Watch landscapes, cultures and even language transform as you cruise along the Mississippi river from Minneapolis to New Orleans aboard the American Queen. Board this 16-day cruise to sail nearly the full length of the mighty Mississippi. Along the way, visit historic port cities and laid-back …
Cruise Details
0
Wander through the historic French Quarter
$3,999
EXPLORE

New Orleans & Southern Charms

8 Day Itinerary aboard Viking Mississippi
  • Enjoy Cajun and Creole cuisine
  • Indulge in New Orleans' music
  • Learn the history of Vicksburg
  • See the historic homes of Natchez
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi overflows with charm, history and hospitality. Wander historic estates, and visit notable Civil War sites. Explore the bustling French-influenced port cities of New Orleans and Baton Rouge. Sway to the tempos of Dixieland jazz, gospel and blues. Savor gourmet Cajun and Creole …
Cruise Details
0
Explore historic New Orleans
$4,299
EXPLORE

Mississippi Holiday Season

Memphis to New Orleans - 8 Day Itinerary aboard Viking Mississippi
  • Enjoy the holidays in New Orleans
  • Explore Memphis's music scene
  • Discover Civil War history
  • See the historic homes of Natchez
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, Festival Visits, River Cruises, Urban Exploration
Activity Level:
Relaxed
Discover the history and charm of the Lower Mississippi on this special holiday season voyage. Cruise from Memphis, where you'll enjoy exclusive Privileged Access to Graceland, decorated for Christmas. Marvel at Christmas light displays and decorated historic homes in Natchez and Baton Rouge; …
Cruise Details
0
Explore historic New Orleans
$4,899
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Duchess
  • Explore the music of Memphis
  • Visit an Antebellum home
  • Learn the history of Vicksburg
  • Enjoy the beauty of Baton Rouge
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, Festival Visits, River Cruises, Urban Exploration
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$2,199
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Queen
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Enjoy a cozy Christmas market with loved ones
$2,199
EXPLORE

Holidays on the River

Memphis to New Orleans - 9 Day Itinerary aboard American Queen
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Embark on a holiday celebration with your American Queen Steamboat Company family, and return with treasured memories of the season. This Lower Mississippi River cruise offers a special Holiday gala, bonfires on the levee, holiday decorations, and performances. Come home to the heart of America and …
Cruise Details
0
Explore historic New Orleans
$2,199
EXPLORE

Roundtrip New Orleans

9 Day Itinerary aboard American Queen
  • Immerse yourself in New Orleans
  • Discover legendary Nottoway
  • Visit historic Civil War sites
  • Visit charming ports and cities
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration
Activity Level:
Relaxed
Discover unique sites and attractions along the Mississippi River and admire the beauty of the world around you on a roundtrip river cruise from New Orleans. Uncover the treasures of Lower Mississippi River cities as you indulge in iconic Louisiana cuisine spiced with the cultural flavors of the …
Cruise Details
0
View a Civil War battlefields in Mississippi
$2,099
EXPLORE

Roundtrip New Orleans

9 Day Itinerary aboard American Countess
  • Admire the beauty of New Orleans
  • Indulge in New Orleans music
  • Experience life at Natchez
  • See preserved historic homes
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Explore unique sites and attractions of the deep south on a river cruise round-trip from New Orleans. Uncover the treasures of Lower Mississippi River cities as you indulge in iconic Louisiana cuisine spiced with influences from the region’s diverse cultures. Visit historic estates and learn …
Cruise Details
0
Nottoway christmas
$1,999
EXPLORE

Holidays on the River

New Orleans to Memphis - 9 Day Itinerary aboard American Duchess
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Celebrate the Christmas season with your American Queen Steamboat Company family and come home with priceless holiday memories. Enjoy a special Christmas banquet, bonfires on the levee, seasonal decorations, and entertainment on the Lower Mississippi River during this trip. Check out some of …
Cruise Details
0
$3,099
EXPLORE

New Orleans to Memphis

9 Day Itinerary aboard American Countess
  • Discover St. Francisville
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore vibrant New Orleans
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$2,975
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Countess
  • Admire the diversity of New Orleans
  • Discover the cultures of the region
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, and an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
View the iconic arch when you visit St. Louis, gateway to the west
$6,999
EXPLORE

Minneapolis to New Orleans

16 Day Itinerary aboard American Countess
  • Explore the arts in Minneapolis, MN
  • Discover St. Louis, Missouri
  • Enjoy musical history in Memphis
  • Learn about Civil War history
  • Admire the diversity of New Orleans
Starts / Ends:
Minneapolis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
As you sail the Mississippi River from Minneapolis to New Orleans aboard the American Countess, observe how landscapes, cultures, and even language change. Sail nearly the whole length of the mighty Mississippi on this 16-day voyage. Visit ancient port cities and sleepy small towns along the way to …
Cruise Details
0
St. Louis' iconic arch at night
$2,559
EXPLORE

St. Louis to Minneapolis

9 Day Itinerary aboard American Queen
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Explore the land and river that inspired legendary American author Samuel Clemens, better known by his pen name, Mark Twain. Cruise northward from St. Louis, Missouri along the mighty Mississippi River, toward the city of Minneapolis. Along the way, explore port towns such as Hannibal, Missouri, …
Cruise Details
0
$2,559
EXPLORE

Minneapolis to St. Louis

9 Day Itinerary aboard American Queen
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Discover the region and river that inspired famed American novelist Samuel Clemens, better known as Mark Twain. On this 9-day cruise onboard American Queen, sail north from St. Louis, Missouri, along the magnificent Mississippi River toward the city of Minneapolis. Along the way, visit port towns …
Cruise Details
0
1-18 of 29 Results

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