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Top Santa Cruz Trips & Tours in September 2025

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Discover Santa Cruz in September 2025 on one of these 281 tours hand-selected by the travel experts at Adventure Life. Explore the best of during September 2025 as you enjoy Wildlife Viewing, Snorkeling, Kayaking, Hiking, and Stand Up Paddle Boarding. Prices for trips in September 2025 range from $265 to $486,550 for a vacation of 5 to 16 days. Choose any of the below 281 itineraries in September 2025 and customize it when you contact one of Adventure Life's expert Santa Cruz trip planners.
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    • Santa Cruz
Elizabeth Bay, Isabela Island, Galapagos, Sea Lion
from $2,670
EXPLORE

Central Islands II

5 Day Itinerary aboard Fragata
  • Relax on Tortuga Bay
  • Visit history places
  • Hike to Dragon Hill
Starts / Ends
Baltra / Baltra
Activity Level
Variable
Discover the stunning landscape of Galapagos aboard Fragata yacht in 5 days, where you enjoy in a panga ride on Black Turtle, snorkeling at red beach on Rabida, learns about history in wall of tears and observe a unique wildlife in Santa Cruz.
Cruise Details
0
Exploring islands of Galapagos
from $2,181
EXPLORE

Walk in Darwin’s Footsteps

4 Day Itinerary
  • See giant tortoise
  • Learn about local conservation
  • Enjoy water activities
  • See wildlife and landscapes
  • See the twin craters of the island
Starts / Ends
Baltra / Baltra
Activities
Wildlife Viewing, Snorkeling, Small Ship Sailing
Activity Level
Relaxed
Enjoy this 4-day island-hopping adventure on Santa Cruz Island, Galapagos. Explore the highlands, visit the Charles Darwin Research Station, and marvel at the Twin Craters. Stay at the luxurious Angermeyer Waterfront Inn, enjoying guided tours that immerse you in the island’s unique beauty.
Tour Details
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Wildlife in the Galapagos
from $6,735
EXPLORE

Galapagos Family Safari Camp

6 Day Itinerary
  • Snorkel at the Galapagos Islands
  • Visit the beautiful Cerro Mesa
  • Discover Garrapatero Beach
  • Enjoy a unique fishing day
Starts / Ends
Santa Cruz / Charles Darwin Center
Activity Level
Relaxed
This incredible 6-day Galapagos family safari offers a variety of activities and engaging educational experiences for both parents and children including a chance to enjoy the exotic beauty of the Galapagos while supporting a fantastic social and conservation initiative such as fishing.
Tour Details
0
Dry Landing at Dragon's Hill
from $4,245
FreeFlight
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Southern Islands II

5 Day Itinerary aboard Galapagos Angel
  • Explore the highlands of Santa Cruz
  • Spot blue-footed boobies
  • Stroll along Gardner Bay
  • Visit Black Turtle Cove
Starts / Ends
Baltra / Baltra
Activity Level
Variable
Explore Santa Cruz's highlands, Suarez Point, Gardner Bay's white-sand beaches, and Santa Fe Island's scenic trails during this 5-day Southern Galapagos cruise aboard the Galapagos Angel. Conclude your journey with a visit to the Dragon Hill, encountering wildlife and relaxation along the way.
Cruise Details
0
Kicker Rock at sunset in the Galapagos
from $6,190
EXPLORE

Southern Islands

5 Day Itinerary aboard M/C Endemic
  • Swim & Kayak at San Cristobal
  • Discover Kicker Rock
  • Visit the Fausto L. Breeding Center
Starts / Ends
Baltra / Baltra
Activity Level
Variable
Sail through the Southern Galapagos Islands, exploring their biodiverse and magical landscapes. Starting in Baltra making your way through Española, San Cristobal, Santa Cruz, Santa Fe, South Plaza and back to Balta.
Cruise Details
0
On our way for another excursion
from $92,390
EXPLORE

Private Charter - Southern Islands Aboard M/C Galapagos Endemic

5 Day Itinerary aboard M/C Endemic
  • Enjoy Kicker Rock's wildlife
  • Visit the Fausto L. Breeding Center
  • Swim & Kayak at San Cristobal
Starts / Ends
Baltra / Baltra
Activity Level
Variable
Sail through the Southeastern Galapagos Islands on a 5-day private cruise. Embark the M/C Endemic in Baltra making your way through Santa Cruz, San Cristobal, Española, Santa Fe, and South Plaza. Overflowing with wildlife, volcanic wonders, and breathtaking landscapes, this is the perfect vacation choice.
Cruise Details
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Sea lion on the beach of Espanola Island
from $4,256
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Northern Islands

5 Day Itinerary aboard Isabela II
  • Ride a zodiac in Tagus Cove
  • Climb Prince Phillip's Steps
  • Explore the cliffs of Isabela
Starts / Ends
Santa Cruz / Baltra
Activity Level
Variable
Get close to giant tortoises on a tour of the Northern Islands. From tortoises to boobies, hawks to sea lions, this northern itinerary makes for a truly memorable 5 days in the Galapagos.
Cruise Details
0
Blue-footed Booby lands on North Seymour Island, Galapagos Islands.
from $6,605
Save 60%
EXPLORE

Exploring Galapagos

10 Day Itinerary aboard National Geographic Endeavour II
  • View endemic wildlife
  • Discover scenic coastlines
  • See varied islands and habitats
  • Experience the Galápagos undersea
Activity Level
Variable
Spend 10 days exploring the legendary Galápagos Islands aboard a classic, 96-guest expedition ship, the Endeavour II. Actively experience the wildlife and wonders of the islands through kayaking, snorkeling, swimming, and hiking.
Cruise Details
0
Visit Kicker Rock, popularly known as the Sleeping Lion (Leon Dormido)
from $3,991
EXPLORE

Galapagos Multisport

Hotel-Based Tour - 8 Day Itinerary
  • Kayak and snorkel among wildlife
  • Learn about Galapagos conservation
  • Cycle to Isabela's coastline
  • Snorkel in Concha Perla
  • Hike the rim of an active caldera
  • View giant Galapagos tortoises
Activities
Biking
Activity Level
Moderate
This 8-day multisport adventure to the Galapagos Islands is packed with thrilling and unique experiences. Begin your action-packed trip with a trek on San Cristobal Island, and then continue with kayaking, snorkeling, and biking around the Galapagos, where wildlife awaits at every turn, trailside, and shoreline!
Tour Details
0
A Marine iguana peaks over a volcanic rock, Galapagos Islands.
from $6,818
EXPLORE

Exploring Galapagos

Ecuador Roundtrip - 10 Day Itinerary aboard National Geographic Gemini
  • Experience wildlife encounters
  • Visit Genovesa
  • See Galapagos penguins
  • Visit giant tortoises
Starts / Ends
Guayaquil / Guayaquil
Activities
Hiking, Kayaking, Whale Watching
Activity Level
Variable
Set sail on a 10-day cruise through the Galapagos Islands aboard the National Geographic Gemini and visit iconic islands like North Seymour, Isabela, and Fernandina. This expedition offers unique experiences, providing an exploration of the legendary Galapagos wildlife.
Cruise Details
0
Wildlife in the Galapagos
from $4,532
EXPLORE

Finch Bay Eco-Hotel

5 Day Itinerary
  • View Giant Tortoises
  • Snorkel along shallow reefs
  • Choose from a menu of activities
Starts / Ends
Baltra / North Seymour
Activities
Village Visits
Activity Level
Relaxed
Set the pace of your Galapagos adventure with a 5-day stay at the Finch Bay Eco-Hotel. Spend your time exploring the natural beauty and wildlife of the islands or relax in the comfort of your seaside hotel. Additional excursions can also be arranged if you wish.
Tour Details
0
Cruise the Galapagos on the Galaxy II ship
from $71,440
EXPLORE

Private Charter - Eastern Islands Aboard EcoGalaxy

6 Day Itinerary aboard EcoGalaxy
  • Swim and snorkel in Bartolome
  • Spot flamingos
  • Hike around Post Office Bay
  • Observe sharks in Gardner Bay
Starts / Ends
Baltra / San Cristobal Airport
Activity Level
Variable
The Eastern Islands of the Galapagos are a great place to experience flamingos, whimbrels, tortoises and more. Board the EcoGalaxy for an incredible 6-day private tour of these islands.
Cruise Details
0
Brilliantly colored flamingos
from $6,195
Savings
EXPLORE

Northern Islands

Baltra roundtrip - 4 Day Itinerary aboard Hermes Ultra Luxury Cruise
  • Spot giant tortoises in Highlands
  • Visit Cerro Dragón and see iguanas
  • Explore Genovesa Island's paradise
Starts / Ends
Baltra / Baltra
Activities
Stand Up Paddle Boarding
Activity Level
Variable
Embark on a 4-day North & Central Islands cruise aboard the Hermes Ultra Luxury Cruise. Observe Santa Cruz Highlands' giant tortoises and lava tunnels. Journey to Dragon Hill, home to land iguanas and flamingos then visit Chinese Hat. Explore El Barranco cliffs and Darwin Bay's bird paradise. Conclude with a marine life excursion in Black Turtle Cove.
Cruise Details
0
Sea lions on Fernandina Island
from $2,700
Savings
EXPLORE

Southern Islands

5 Day Itinerary aboard Bonita
  • Hike over islands covered in cacti
  • Kayak and stand up paddle board
  • Admire distinctive biodiversity
Starts / Ends
Highlands / Bachas Beach
Activity Level
Variable
This 5-day cruise of Galapagos' Southern Islands on the Bonita yacht explores the islands of Espanola, Santa Cruz, San Cristobal and more. Kayak and paddle board along island shores, swim and snorkel among sea lions, and enjoy breathtaking views on hikes.
Cruise Details
0
Bonita Galapagos Yatch
from $41,040
EXPLORE

Private Charter - Southern Islands Aboard Bonita

5 Day Itinerary aboard Bonita
  • Hike over islands covered in cacti
  • Kayak and stand up paddle board
  • Admire distinctive biodiversity
Starts / Ends
Highlands / Bachas Beach
Activity Level
Variable
This 5-day private cruise of Galapagos' Southern Islands on the Bonita yacht explores the islands of Espanola, Santa Cruz, San Cristobal and more. Kayak and paddle board along island shores, swim and snorkel among sea lions, and enjoy breathtaking views on hikes.
Cruise Details
0
Land Iguana in the Galapagos
from $5,995
from $5495
EXPLORE

Wildlife Discovery

San Cristobal - Baltra - 5 Day Itinerary aboard Tribute
  • Observe blue-footed boobies
  • Explore Black Turtle Cove
  • Get surprised by curious sea lions
  • Visit Darwin Research Station
Starts / Ends
San Cristobal Airport / Baltra
Activity Level
Variable
Explore Central & North Galapagos in a 5-day Wildlife Discovery cruise aboard Tribute. Encounter sea lions, blue-footed boobies, frigate birds, Galapagos hawks, diverse marine life, and giant tortoises at Darwin Research Station. Enjoy close encounters snorkeling with penguins, and turtles, and witness nature's wonders in diverse island habitats.
Cruise Details
0
A kayaking trip to see the local bird life of the Galapagos.
from $9,400
up to 40%
EXPLORE

In the Steps of Darwin

8 Day Itinerary aboard Evolution
  • Discover Daphne Major´s birdlife
  • Snorkel on Isabela Island
  • Meet Urbina´s Bay unique wildlife
  • Walk the white beach of Las Bachas
Starts / Ends
Baltra / San Cristobal Interpretation Center
Activity Level
Variable
Discover all of the Galapagos wildlife that made the Islands famous and inspired Charles Darwin´s theory of evolution. Snorkel, swim, or kayak on the pristine crystal waters and experience amazing animal encounters, including playful sea lions, frigate birds, iguanas, blue footed boobies, penguins, and giant tortoises.
Cruise Details
0
Couple sitting on a beach among sea lions
from $9,990
EXPLORE

South & Central Islands

8 Day Itinerary aboard M/C Endemic
  • Dive & Snorkel around Kicker Rock
  • Lounge alongside sleeping sea lions
  • Walk along a white coral sand beach
  • Learn the history of Floreana
Activity Level
Variable
Enjoy the beauty of Bartolome, Española, Floreana, Mosquera Islet, North Seymour, San Cristobal, Santa Cruz, Santa Fe, Santiago and South Plaza on this 8-day Galapagos cruise aboard the M/C Endemic. On this cruise of the South and Central Islands, you'll have daily opportunities to hike, snorkel, kayak, and explore the incredible biodiversity of Galapagos!
Cruise Details
0
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