Top Mediterranean Tours & Cruises in 2025

from $16,172

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Mediterranean Wonders: Sicily, Greece, Sardinia, and Beyond

Spain - Greece - 13 Day Itinerary aboard National Geographic Orion

Starts / Ends

Barcelona / Athens

Activities

Hiking, Land & Sea Exploration, Kayaking, Stand Up Paddle Boarding

Activity Level

Variable

On this 13-day Mediterranean Wonders Cruise from Spain to Greece aboard National Geographic Orion, explore ancient ruins, medieval towns, and culinary delights. Visit Menorca's prehistoric stones, savor Sicilian wine, swim in Kefalonia's waters, and explore Delphi.

• Cruise the Mediterranean Sea
• Explore standing stones on Menorca
• Taste Sicilian wine
• Swim at Kefalonia
• Explore Delphi and Corinth Canal

Cruise Details

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from $9,100

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Cruising the Greek Islands of the Southern Aegean: with Smithsonian Journeys

Roundtrip Athens - 8 Day Itinerary aboard Le Dumont-d'Urville

Starts / Ends

Athens / Athens

Activity Level

Variable

Take a cruise for eight days to some of the most stunning Greek islands in the southern Aegean by boarding the opulent L'Austral in Athens. Before returning to Athens, visit the city of Delos, Mykonos, Hydra, and Patmos.

• Smithsonian Journeys Cruise
• Explore UNESCO World Heritage Sites
• Sail the Santorini Caldera
• Explore Mykonos

Cruise Details

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from $6,799

Air Credit

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Vintage Coves and Isles

Barcelona - Athens - 13 Day Itinerary aboard World Navigator

Starts / Ends

Barcelona / Piraeus

Activities

Urban Exploration

Activity Level

Variable

Join a 13-day trip from Barcelona to Athens aboard World Navigator, exploring France, Italy, and Greece. Discover Barcelona’s architecture, visit Roses and Cadaques, and enjoy a winery tour. Explore Sete, Saint-Tropez, and Cinque Terre. From Livorno, visit Florence and Pisa, then explore Rome, Sorrento, and Lipari. End in Crete, Hydra, and Athens.

• Discover key landmarks of Barcelona
• Learn about Roses, Cadaques culture
• Visit a number of coastal villages
• Explore Tuscany, Pisa and Rome

Cruise Details

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from $1,940

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Amalfi & Sicily

7 Day Itinerary aboard Star Flyer

Starts / Ends

Civitavecchia / Civitavecchia

Activity Level

Variable

Board the Star Flyer on this unforgettable 7-day cruise of the Mediterranean. Admire the perfect architecture and magical landscapes this region is famous for, visiting Ponza, Amalfi, Lipari, and more! Explore the Sistine Chapel and wander through the town of Pontine Islands.

• Explore Civitavecchia
• Discover Lipari
• Explore Amalfi
• Discover Messina

Cruise Details

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from $4,500

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Grand Voyage: Nice to Las Palmas

17 Day Itinerary aboard Star Flyer

Starts / Ends

Nice / Las Palmas

Activity Level

Variable

Embark on a 17-day voyage aboard Star Clippers. Explore Spain, Morocco, and the Canary Islands, visiting iconic cities like Nice, Tangier, and Las Palmas. Experience Moorish architecture, vibrant ports, and tranquil days at sea.

• Explore Promenade des Anglais
• Explore Palma de Mallorca
• Stroll Ibiza historic old town
• Visit Cartagena Roman ruins

Cruise Details

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from $1,630

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Rome to Rome

Civitavecchia Roundtrip - 6 Day Itinerary aboard Star Flyer

Starts / Ends

Civitavecchia / Civitavecchia

Activity Level

Variable

Sail on a 6-day Italy cruise with Star Flyer, exploring Rome's iconic landmarks, visiting Gaeta's historic coastal city, and discovering the medieval charm of Amalfi. Explore Positano, marvel at Sorrento's city walls, and enjoy the unspoiled beauty of Ponza Town before concluding the journey in Civitavecchia.

• Visit the Sistine Chapel
• Explore Gaeta's history
• Discover the town of Positano
• Witness the pastel houses of Ponza

Cruise Details

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from $4,699

Air Credit

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Iconic Spain and Iberia

Lisbon - Barcelona - 8 Day Itinerary aboard World Navigator

Starts / Ends

Lisbon / Barcelona

Activity Level

Variable

Embark on an 8-day cruise from Lisbon to Barcelona aboard World Navigator and visit vibrant cities like Portimao, Cadiz, and Cartagena. Discover historic landmarks, cultural treasures, and breathtaking natural scenery on this unforgettable adventure across the Mediterranean.

• Experience Lisbon tuk-tuk adventure
• Relax at Portimao’s famous beach
• Explore Donana National Park
• Walk through the vibrant Park Guell

Cruise Details

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from $6,800

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Classic Croatian Adventure

Zagreb to Dubrovnik - 14 Day Itinerary

Starts / Ends

Zagreb / Dubrovnik

Activities

Cooking Classes

Activity Level

Relaxed

This 14-day Classic Croatian Adventure for 2025 takes visitors on a cultural and culinary journey by land and sea. Explore vibrant Zagreb, marvel at the UNESCO-listed Plitvice Lakes National Park, and the stunning old city of Split. Sail to the renowned islands of Hvar and Korcula, and culminate your voyage in magical Dubrovnik.

• Visit Zagreb with guide
• See lakes and stunning waterfalls
• Sail the coastline of Split
• Visit the Diocletian's Palace
• Visit Dubrovnik's historical places
• Visit an Oyster Farm in Ston
• Visit Hvar, a popular island escape

Tour Details

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from $12,790

2for1

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Greek Islands & Turkish Coastline

Roundtrip Athens - 8 Day Itinerary aboard Emerald Azzurra

Starts / Ends

Athens / Athens

Activity Level

Variable

Set sail on an 8-day cruise from Athens aboard the Emerald Azzurra, discovering Greece and Turkey's coastal gems. Experience ancient sites like Delos and Mykonos, enjoy leisure in Santorini, and explore local markets, all while relaxing on your luxurious yacht.

• Explore Athens' sophistication
• Discover Delos' mythological past
• Experience Mykonos' whitewashed
• Visit Patmos’ sacred cave

Cruise Details

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from $2,840

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Morocco & Canary Islands

Malaga - Las Palmas - 10 Day Itinerary aboard Star Clipper

Starts / Ends

Malaga / Las Palmas

Activity Level

Variable

Embark on a 10-day Star Clippers cruise through Spain, Morocco, and the Canary Islands. Highlights include Malaga’s Alhambra, Gibraltar’s iconic Rock, Tenerife’s Mount Teide, and the colonial charm of Las Palmas.

• Explore Malaga’s Alhambra Palace
• Visit Gibraltar’s iconic Rock
• Discover Tangier’s cosmopolitan
• Stroll Las Palmas’ colonial streets

Cruise Details

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from $14,030

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The Cyclades, in the Wake of Le Ponant

Roundtrip Athens - 8 Day Itinerary aboard Le Ponant

Starts / Ends

Tinos / Kythnos

Activities

Snorkeling

Activity Level

Variable

Embark on an 8-day cruise aboard Le Ponant roundtrip from Athens. Sail from Lavrio port to the Cyclades, exploring Tinos and Polyaigos. Enjoy strolls on Serifos before heading southeast to discover Monemvasia's peninsula. Sail towards Kythnos, a rugged terrain. Spetses, "the island of Jasmine," offers tailored activities.

• Discover Kythnos
• Visit Monemvasia
• Experience Serifos
• Discover the island of Polyaigos

Cruise Details

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from $7,099

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Grande Italia

Milan to Rome - 13 Day Itinerary aboard S.S. La Venezia

Starts / Ends

Milan / Rome

Activities

Biking

Activity Level

Variable

Experience the best of Northern Italy with a journey through Milan, Verona, and Venice on this 13-day Grande Italia cruise aboard S.S. La Venezia. Explore Verona, the romantic city of Romeo and Juliet, and enjoy a wine tasting at a historic Valpolicella estate. Sail through the Venetian Lagoon, and experience the grandeur of Castello del Catajo.

• Marvel at Milan’s Duomo
• Walk historic Verona streets
• Discover colorful Burano
• Watch Murano glassblowers

Cruise Details

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from $7,990

2for1

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Sensations of Lyon and Provence

Lyon - Marseille - 8 Day Itinerary aboard Emerald Liberté

Starts / Ends

Lyon / Marseille

Activity Level

Variable

Sail from Marseille to Lyon for another fun and exciting 8-day cruise along the Rhone and Saone Rivers. Emerald Liberté offers comfortable accommodations before exploring different cities.

• Explore Lyon
• Discover Chalon-sur-Saône
• Experience Tournon
• Uncover the rich history of Arles

Cruise Details

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from $7,356

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Lake Como, Milan, and Amalfi

10 Day Itinerary

Starts / Ends

Milan / Naples

Activity Level

Relaxed

Discover Italy’s highlights on this 10-day tour, from Lake Como and exploring Milan’s Gothic splendor to savoring limoncello in Amalfi. Visit Pompeii’s ancient ruins and unwind on the stunning Amalfi Coast.

• Ride a boat on Lake Como
• See the Gothic Art in Milan
• Stroll around in Galleria Vittorio
• See archaeological sites in Pompeii
• Admire the coastline of Amalfi
• Enjoy scenic drives in Italy

Tour Details

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from $9,995

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A Maritime Fairy Tale from 1001 Nights

11 Day Itinerary aboard Sea Cloud II

Starts / Ends

Malaga / Las Palmas

Activities

Wine Tasting, Local Market Visits, Small Ship Sailing

Activity Level

Variable

Sail from Malaga to Las Palmas on this 11-day Sea Cloud II cruise. Explore Cadiz, Seville, Tangier, Casablanca, Rabat, Agadir, Lanzarote, and more. Enjoy scenic sailing days, visit Chefchaouen’s blue streets, and discover culture, history, and nature across Spain, Morocco, and the Canary Islands.

• Enjoy top cities Cadiz and Seville
• Experience highlights of Morocco
• Stroll Chefchaouen’s blue streets
• Explore volcanoes and unique arts

Cruise Details

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from $2,084

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Andalusia: Tradition, Gastronomy, and Flamenco

Seville Roundtrip - 8 Day Itinerary aboard MS La Belle de Cadix

Starts / Ends

Seville / Seville

Activity Level

Variable

This 8-day Spanish cruise aboard the MS La Belle de Cadix showcases the Andalusia region, including stops in Seville, Cadiz, Granada and Cordoba. Local wine tastings, Flamenco music and visits to the UNESCO Biosphere Reserve Donana Park highlight this itinerary.

• Sail across the Guadalquivir River
• View a traditional equestrian show
• Explore Jerez, the capital of wine
• Visit the charming city of Granada

Cruise Details

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from $7,120

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Westbound Atlantic Ocean Crossing

Civitavecchia - Bridgetown - 29 Day Itinerary aboard Royal Clipper

Starts / Ends

Civitavecchia / Bridgetown

Activity Level

Variable

Set sail on a 29-day cruise aboard the Royal Clipper, traveling from Civitavecchia to the Caribbean while exploring historic and vibrant locations like Bonifacio, Ibiza, and Malaga. Enjoy days at sea, classic sailing experiences, and onboard activities before reaching Barbados.

• Explore Bonifacio’s scenic harbor
• Discover Mahon’s Georgian charm
• Wander Palma’s markets
• Unwind on Ibiza’s beaches

Cruise Details

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from $4,020

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Grand Voyage: Las Palmas to Cannes

Las Palmas - Cannes - 13 Day Itinerary aboard Royal Clipper

Starts / Ends

Las Palmas / Cannes

Activities

Wildlife Viewing, Village Visits, Archaeological Site Visits

Activity Level

Variable

Embark on a 13-day cruise aboard the Royal Clipper through the Canary Islands, Morocco, Spain, and Monaco. Starting in Las Palmas, experience art, vibrant markets, historical sites, and beautiful beaches, and end in Cannes after visiting the highlights of each destination.

• Explore Las Palmas landscapes
• Wander Safi's historic streets
• Visit Casablanca’s Hassan II Mosque
• Discover Fuerteventura's streets

Cruise Details

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