Top Panama Canal Tours & Cruises in 2025

This Panama City one-day tour takes you on the incredible journey from the Atlantic Ocean all the way to the Pacific Ocean, traversing two impressive locks via the manmade wonder that is the Panama Canal.

Climb aboard and experience the "Eighth Wonder of the World" first hand as you transit through the Miraflores Locks to the Pacific Ocean.

Tour Panama City with a local guide, well versed in the history of the area. See a transit of the Panama canal and tour Casco Antiguo where the pirate Henry Morgan waged his attack in 1671.

Visit Aguas Clara Visitor Center for stunning Gatun Lake views and marvel at the historic San Lorenzo Fort. Explore scenic landscapes, rich wildlife, and Panama Canal expansion highlights in one action-packed day.

Begin your Panama journey at the manmade marvel, the Panama Canal, and continue your travels into the region's tropical forests, visiting an indigenous community in Chagres National Park and exploring the ecology of Barro Colorado Island. This is a great introductory tour of Panama!

Experience the Caribbean from Costa Rica to Panama on this 9-day land-based adventure tour. Whitewater rafting and rainforest exploration along Costa Rica's Pacuare River combine with relaxation amidst the turquoise waters of Panama. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and snorkel & dive among the Caribbean reefs!

This 8-day hotel-based tour of Panama takes you from metropolitan Panama City, through the lowland tropical forest of Soberania National Park, snorkeling, kayaking, hiking, surfing, birding, and exploring Bocas del Toro & Tranquilo Bay, and finally to the Miraflores locks of the Panama Canal.

Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.

Discover Costa Rica & Panama on this wonderful 8-day expedition cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.

Set sail on a 15-day cruise with Star Clipper from Bridgetown, Barbados, exploring the Caribbean’s rich culture and history, ending in Balboa, Panama. Visit stunning destinations like Tobago Cays, Grenada, and the San Blas Islands, and experience the Panama Canal.

Set sail on a 15-day Royal Clipper cruise from Balboa, Panama, featuring a full Panama Canal transit and visits to the San Blas Islands, Cartagena, and the Caribbean gems of Aruba, Curacao, and Bonaire. Experience lush Grenada and volcanic St. Lucia, and finish your journey in Antigua, all while enjoying elegant sailing and stunning island views.

Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, Archipelago, and more.