Top Panama Tours & Cruises in 2027

Choose a 9-day Panama National Parks and Beaches tour, and discover Old Panama ruins, iconic Canal views, lush waterfalls, and thrilling zip line adventures. Experience history, nature, and excitement in one unforgettable journey.

Discover unique wildlife in the vibrant jungles of western Panama as well as charming Caribbean towns through this comprehensive Panama tour. Explore the country through rainforest hikes, urban explorations, and snorkeling outings. Enjoy a remarkable and truly fresh cup of locally grown coffee at the end of the day!

Begin your Panama journey at the manmade marvel, the Panama Canal, and continue your travels into the region's tropical forests, visiting an indigenous community in Chagres National Park and exploring the ecology of Barro Colorado Island. This is a great introductory tour of Panama!

This 8-day land-based tour highlights the best of Costa Rica and Panama! Whitewater excitement and rainforest exploration in Costa Rica couple with relaxation amidst the turquoise waters of Panama for a perfectly paced vacation. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and fall into the rhythm of the Caribbean!

Experience the Caribbean from Costa Rica to Panama on this 9-day land-based adventure tour. Whitewater rafting and rainforest exploration along Costa Rica's Pacuare River combine with relaxation amidst the turquoise waters of Panama. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and snorkel & dive among the Caribbean reefs!

Discover Panama with our 9-day itinerary! Immerse yourself in the allure of Boquete's charming town, indulge in the unique experiences at Nayara Bocas del Toro, unwind on pristine beaches, and culminate your journey with a captivating Panama City tou

Embark on an 8-day Panama Canal, Pearl Islands and Darien Jungle cruise aboard National Geographic. Quest in Colon and explore Panama’s Pacific coast. Cruise Gatun Lake, hike Barro Colorado Island trails, and visit the Pearl Islands. Discover Darien National Park’s rainforest and culture, explore Punta Patiño Reserve, and return to Panama City.

Explore Panama on an 8-day cruise aboard National Geographic Quest. Transit the Panama Canal, anchor in Gatun Lake, and discover Darien National Park and the Pearl Islands. Kayak, hike rainforests, snorkel reefs, and meet Embera communities in remote villages and protected reserves.

Explore Panama and Costa Rica on this 8-day voyage from Colón to Puntarenas aboard Le Laperouse. Travel through the Panama Canal, visit the San Blas Islands, Portobelo and Darién National Park, and discover local communities, coastal landscapes and wildlife. The journey also includes time at sea and excursions in Costa Rica’s Osa Peninsula region.

Discover Costa Rica & Panama on this 8-day cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.

Discover Panama's allure with a day exploring Aguas Clara, San Lorenzo Fort, and Portobelo's historic port. Snorkel along picturesque bays and witness colonial charm, designated a UNESCO Patrimony for Humanity.

Explore Panama and Costa Rica aboard Le Bellot on an 11-day cruise. Sail through the Panama Canal, visit Fort San Lorenzo, the San Blas Islands, Pearl Islands, Darién National Park, Coiba Island, Rio Esquinas, Drake Bay, and Curú Wildlife Refuge. Experience wildlife viewing, Zodiac landings, and cultural encounters with indigenous communities.